Exploring the Link Between Estrogen and Migraines

Exploring the Link Between Estrogen and Migraines

Exploring the Link Between Estrogen and Migraines

Study sees big drop in levels of the female hormone in the days before menstruation

SOURCE: Neurology, news release, June 1, 2016

WEDNESDAY, June 1, 2016 (HealthDay News) -- Researchers are getting a better understanding of the link between estrogen levels and migraine headaches in women.

A new study finds that for women who get these intense headaches, levels of the hormone estrogen drop more rapidly in the days before menstruation than in women without the headaches.

"These results suggest that a 'two-hit' process may link estrogen withdrawal to menstrual migraine," said study author Dr. Jelena Pavlovic, of the Albert Einstein College of Medicine/Montefiore Medical Center in New York City. "More rapid estrogen decline may make women vulnerable to common triggers for migraine attacks such as stress, lack of sleep, foods and wine."

Researchers looked at urine samples of 114 women with migraines and 223 women without migraines, average age 47. Estrogen levels among those with migraines dropped 40 percent in the days just before menstruation, compared to 30 percent for those without migraines, the study found.

No similar patterns were seen with other types of hormones, according to the study.

The results were published online June 1 in the journal Neurology.

"Future studies should focus on the relationship between headaches and daily hormone changes and explore the possible underpinnings of these results," Pavlovic added in a journal news release.

About 12 percent of Americans get migraines, and they're three times more common in women than men, according to the American Migraine Foundation. Besides headaches, migraine attacks can include nausea, vomiting and sensitivity to lights, sound and smells.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about migraine.

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