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Durvalumab and Tremelimumab for Pediatric Malignancies

The purpose of the study is to determine the recommended dose of durvalumab and tremelimumab (immunotherapy drugs) in pediatric patients...

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Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy

Bowel preparation for pediatric colonoscopy.

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Predictive Mini-bolus Fluid Responsiveness in Pediatric Septic Shock

Severe sepsis and septic shock remain of particular gravity in children with a current mortality of about 20 % ,...

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Pediatric Patients With Metabolic or Other Genetic Disorders

Background: Some patients with unusual genetic conditions are referred to the National Institutes of Health (NIH). They may not be...

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Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with...

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A Study of Tildrakizumab in Pediatric Subjects With Chronic Plaque Psoriasis

The study has been designed with three components. Part A is an open label PK study followed by a randomized...

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67Cu-SARTATE™ Peptide Receptor Radionuclide Therapy Administered to Pediatric Pa...

The aim of this study is to evaluate the safety and efficacy of 67Cu-SARTATE in pediatric patients with high-risk neuroblastoma.

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Study of Safety and Efficacy of CFZ533 in Type 1 Diabetes Pediatric and Young Ad...

The study is a Phase 2, multicounty, multicenter, non-confirmatory, investigator- and subject masked, randomized, placebo-controlled study to evaluate the safety,...

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Efficacy and Safety of Erenumab in Pediatric Subjects With Episodic Migraine

This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and...

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Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in P...

Multicenter, open-label, non-comparative study to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of osilodrostat in children and adolescent patients with ...

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A Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidis...

This is a Phase 3 Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

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Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis

To evaluate the safety and efficacy of fingolimod vs. interferon beta-1a i.m. in pediatric patients with multiple sclerosis (MS)

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Risk Factors, Clinical Characteristics and Outcomes of Acute Infection With Coro...

Patient are being asked to provide respiratory and blood samples for a clinical research study because the patients have a...

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CLCZ696B2319E1 OL Extension Study to Evaluate Long-term Safety of Sacubitril/Val...

The purpose of this study is to evaluate long-term safety and tolerability data in eligible CLCZ696B2319 (PANORAMA-HF) patients receiving open-label...

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A Study of Recombinant Von Willebrand Factor (rVWF) in Pediatric and Adult Parti...

The main aim of the study is to check effectiveness of rVWF (vonicog alfa) prophylaxis based on the annualized bleeding...

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Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Chi...

This study is conducted in China only. The purpose is to demonstrate the efficacy and safety of once weekly dosing...

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A Roll-over Study With Rilpivirine for Human Immunodeficiency Virus Type 1 (HIV-...

The purpose of this study is to provide continued access to rilpivirine (RPV) for participants who were treated with RPV...

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A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterf...

This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS)...

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A Study to Assess the Safety, Tolerability and Preliminary Efficacy of ASP0367 (...

The primary purpose of this study is to evaluate the safety and tolerability of ASP0367. This study will also evaluate...

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Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in I...

The primary objective of the study is to demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C,...

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Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccin...

Primary objective is to demonstrate the non-inferiority of the antibody response against meningococcal serogroups A, C, Y, and W following...

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A Safety Study of Ustekinumab in the Treatment of Pediatric Participants Aged 6...

The purpose of this study is to monitor the long-term safety of ustekinumab in pediatric participants (6 years to 17...

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Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketam...

The purpose of this study is to assess the efficacy of a single (first) dose of 3 fixed doses of...

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Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Dis...

This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged ≥ 2 to <...