This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and...
The purpose of the study is to determine the recommended dose of durvalumab and tremelimumab (immunotherapy drugs) in pediatric patients...
To evaluate the effect of denosumab on lumbar spine bone mineral density (BMD) Z-score as assessed by dual-energy X-ray absorptiometry...
This study will evaluate the long-term safety and hemostatic efficacy of recombinant von Willebrand factor (rVWF) (vonicog alfa) prophylaxis in...
AMG 334 20160172 Pediatric Migraine PK Study.
This phase 3 clinical study is a randomized, observer-blind, multicenter study of QIVc versus a non-influenza vaccine in subjects 6...
This is a multicenter, open-label, single-dose pharmacokinetic (PK) study. Infants, children, and adolescents will receive a single 10 mg/kg dose...
Background: Some patients with unusual genetic conditions are referred to the National Institutes of Health (NIH). They may not be...
This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with...
This is a multi-center, open-label, international study to evaluate the dose, safety and tolerability, antitumor activity, pharmacokinetic and pharmacodynamics of...
Primary Objectives: - To describe the characteristics of pediatric patients with moderate to severe atopic ...
The purpose of the Phase 2 CSEG101B2201 study is to confirm and to establish appropriate dosing and to evaluate the...
Multicenter, open-label, non-comparative study to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of osilodrostat in children and adolescent patients with ...
Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
Primary Objective: To explore associations between biomarkers of atopic dermatitis (AD) and: -...
To demonstrate the safety of 1% OPA-15406 ointment in adult patients with AD and of 0.3% and 1% OPA-15406 ointments...
The study has been designed with two components. Part A is an open label PK study followed by a randomized...
Patient are being asked to provide respiratory and blood samples for a clinical research study because the patients have a...
CV185118 is a single dose Apixaban PK/PD study in pediatric participants. The objective of this study is primarily to study...
This phase I trial studies the side effects and best dose of nanoparticle albumin-bound rapamycin when given together with temozolomide...
The purpose of this study is to evaluate long-term safety and tolerability data in eligible CLCZ696B2319 (PANORAMA-HF) patients receiving open-label...
This study is conducted in China only. The purpose is to demonstrate the efficacy and safety of once weekly dosing...
The purpose of this study is to determine if the investigational treatment, MHOS/SHP615, is safe and effective in children with...
The study is an open-label, single-arm, Phase I/II multi-center study to investigate the PK, activity and safety of ruxolitinib added...
The purpose of this study is to provide continued access to rilpivirine (RPV) for participants who were treated with RPV...
The main objective of the study is to evaluate the efficacy of dimethyl fumarate (Tecfidera) and peginterferon beta-1a (Plegridy), both...
The purpose of this study is to monitor the long-term safety of ustekinumab in pediatric participants (12 years to 17...
This open-label, single-arm, Phase II multi-center study will enroll approximately 42 subjects and investigate the activity, pharmacokinetics and safety of...
The primary objective of the study is to demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C,...
Primary Objective: 1. To describe the antibody titers to the antigens (meningococcal serogroups A, C, Y, and ...
The primary objective of the study is to demonstrate the non-inferiority of the antibody response against meningococcal serogroups A, C,...
This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS)...
To investigate the safety and pharmacokinetics of apixaban in children with congenital or acquired heart disease who have a need...
The purpose of this study is to assess the efficacy of a single (first) dose of 3 fixed doses of...
Bowel preparation for pediatric colonoscopy.
This is a Phase 2 study to evaluate the safety and efficacy of autologous CD30.CAR-T in subjects with relapsed or...
The aim of this study is to evaluate the safety and efficacy of 67Cu-SARTATE in pediatric patients with high-risk neuroblastoma.
The purpose of this study is to assess the safety and effectiveness of treatment with once daily (QD) oral administration...
The purpose of this study is to assess the safety and effectiveness of treatment with once daily (QD) oral administration...
Primary Objective: To demonstrate the non-inferiority of the SHAN6™ vaccine to the licensed SHAN5™ given with ...
The purpose of this study is to compare the effect of ticagrelor vs placebo for the reduction of Vaso-Occlusive crises...
The primary purpose of this study is to evaluate the safety, tolerability and preliminary efficacy of ASP0367. ...
This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged ≥ 2 to <...
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