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Efficacy and Safety of Erenumab in Pediatric Subjects With Episodic Migraine

This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and...

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Durvalumab and Tremelimumab for Pediatric Malignancies

The purpose of the study is to determine the recommended dose of durvalumab and tremelimumab (immunotherapy drugs) in pediatric patients...

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Safety and Efficiency of Denosumab in Pediatric Subjects With Glucocorticoid-ind...

To evaluate the effect of denosumab on lumbar spine bone mineral density (BMD) Z-score as assessed by dual-energy X-ray absorptiometry...

Enrolling

rVWF Pediatric and Adult Study

This study will evaluate the long-term safety and hemostatic efficacy of recombinant von Willebrand factor (rVWF) (vonicog alfa) prophylaxis in...

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AMG 334 20160172 Pediatric Migraine PK Study.

AMG 334 20160172 Pediatric Migraine PK Study.

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Efficacy Study With QIVc in Pediatric Subjects

This phase 3 clinical study is a randomized, observer-blind, multicenter study of QIVc versus a non-influenza vaccine in subjects 6...

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Telavancin Pediatric PK Study (Ages >3 Months to 17 Years)

This is a multicenter, open-label, single-dose pharmacokinetic (PK) study. Infants, children, and adolescents will receive a single 10 mg/kg dose...

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Pediatric Patients With Metabolic or Other Genetic Disorders

Background: Some patients with unusual genetic conditions are referred to the National Institutes of Health (NIH). They may not be...

Enrolling

Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with...

Enrolling

Phase I/II Study of Avelumab in Pediatric Cancer Subjects

This is a multi-center, open-label, international study to evaluate the dose, safety and tolerability, antitumor activity, pharmacokinetic and pharmacodynamics of...

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Observational Evaluation of Atopic Dermatitis in Pediatric Patients

Primary Objectives: - To describe the characteristics of pediatric patients with moderate to severe atopic ...

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Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell...

The purpose of the Phase 2 CSEG101B2201 study is to confirm and to establish appropriate dosing and to evaluate the...

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Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in P...

Multicenter, open-label, non-comparative study to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of osilodrostat in children and adolescent patients with ...

Enrolling

Study of Etelcalceide in Pediatric Subjects With Secondary Hyperparathyroidism a...

Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

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Evaluation of Biomarkers of Atopic Dermatitis in Pediatric Patients (PEDISTAD BI...

Primary Objective: To explore associations between biomarkers of atopic dermatitis (AD) and: -...

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Long-term Trial of OPA-15406 Ointment in Adult and Pediatric Patients With Atopi...

To demonstrate the safety of 1% OPA-15406 ointment in adult patients with AD and of 0.3% and 1% OPA-15406 ointments...

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A Study of Tildrakizumab in Pediatric Subjects With Chronic Plaque Psoriasis

The study has been designed with two components. Part A is an open label PK study followed by a randomized...

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Risk Factors, Clinical Characteristics and Outcomes of Acute Infection With Coro...

Patient are being asked to provide respiratory and blood samples for a clinical research study because the patients have a...

Enrolling

Study to Evaluate a Single Dose of Apixaban in Pediatric Participants at Risk fo...

CV185118 is a single dose Apixaban PK/PD study in pediatric participants. The objective of this study is primarily to study...

Enrolling

Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride...

This phase I trial studies the side effects and best dose of nanoparticle albumin-bound rapamycin when given together with temozolomide...

Enrolling

CLCZ696B2319E1 OL Extension Study to Evaluate Long-term Safety of Sacubitril/Val...

The purpose of this study is to evaluate long-term safety and tolerability data in eligible CLCZ696B2319 (PANORAMA-HF) patients receiving open-label...

Enrolling

Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Chi...

This study is conducted in China only. The purpose is to demonstrate the efficacy and safety of once weekly dosing...

Enrolling

Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric...

The purpose of this study is to determine if the investigational treatment, MHOS/SHP615, is safe and effective in children with...

Enrolling

Study of Pharmacokinetics, Activity and Safety of Ruxolitinib in Pediatric Patie...

The study is an open-label, single-arm, Phase I/II multi-center study to investigate the PK, activity and safety of ruxolitinib added...

Enrolling

A Roll-over Study With Rilpivirine for Human Immunodeficiency Virus Type 1 (HIV-...

The purpose of this study is to provide continued access to rilpivirine (RPV) for participants who were treated with RPV...

Enrolling

Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and P...

The main objective of the study is to evaluate the efficacy of dimethyl fumarate (Tecfidera) and peginterferon beta-1a (Plegridy), both...

Enrolling

A Safety Study of Ustekinumab in the Treatment of Pediatric Participants Aged 12...

The purpose of this study is to monitor the long-term safety of ustekinumab in pediatric participants (12 years to 17...

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Activity, Safety and Pharmacokinetics in Pediatric Subjects With Moderate and Se...

This open-label, single-arm, Phase II multi-center study will enroll approximately 42 subjects and investigate the activity, pharmacokinetics and safety of...

Enrolling

Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in I...

The primary objective of the study is to demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C,...

Enrolling

Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When...

Primary Objective: 1. To describe the antibody titers to the antigens (meningococcal serogroups A, C, Y, and ...

Enrolling

Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccin...

The primary objective of the study is to demonstrate the non-inferiority of the antibody response against meningococcal serogroups A, C,...

Enrolling

A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterf...

This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS)...

Enrolling

A Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagoni...

To investigate the safety and pharmacokinetics of apixaban in children with congenital or acquired heart disease who have a need...

Enrolling

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketam...

The purpose of this study is to assess the efficacy of a single (first) dose of 3 fixed doses of...

Not Yet Enrolling

Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy

Bowel preparation for pediatric colonoscopy.

Not Yet Enrolling

Phase 2 Study Evaluating Autologous CD30.CAR-T Cells in Adult and Pediatric Pati...

This is a Phase 2 study to evaluate the safety and efficacy of autologous CD30.CAR-T in subjects with relapsed or...

Not Yet Enrolling

67Cu-SARTATE™ Peptide Receptor Radionuclide Therapy Administered to Pediatric Pa...

The aim of this study is to evaluate the safety and efficacy of 67Cu-SARTATE in pediatric patients with high-risk neuroblastoma.

Not Yet Enrolling

A Phase 2, Double Blind Study to Assess Dexlansoprazole Delayed-Release Capsules...

The purpose of this study is to assess the safety and effectiveness of treatment with once daily (QD) oral administration...

Not Yet Enrolling

A Phase 2 Study of Dexlansoprazole Delayed-Release Capsules to Treat Symptomatic...

The purpose of this study is to assess the safety and effectiveness of treatment with once daily (QD) oral administration...

Not Yet Enrolling

Study of DTwP-HepB-Hib-IPV (SHAN6™) Vaccine Administered Concomitantly With Rout...

Primary Objective: To demonstrate the non-inferiority of the SHAN6™ vaccine to the licensed SHAN5™ given with ...

Not Yet Enrolling

Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlu...

The purpose of this study is to compare the effect of ticagrelor vs placebo for the reduction of Vaso-Occlusive crises...

Not Yet Enrolling

A Study to Assess the Safety, Tolerability and Preliminary Efficacy of ASP0367 (...

The primary purpose of this study is to evaluate the safety, tolerability and preliminary efficacy of ASP0367. ...

Not Yet Enrolling

Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Dis...

This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged ≥ 2 to <...