The purpose of the study is to determine the recommended dose of durvalumab and tremelimumab (immunotherapy drugs) in pediatric patients...
Severe sepsis and septic shock remain of particular gravity in children with a current mortality of about 20 % ,...
This study will evaluate the long-term safety and hemostatic efficacy of recombinant von Willebrand factor (rVWF) (vonicog alfa) prophylaxis in...
AMG 334 20160172 Pediatric Migraine PK Study.
This phase 3 clinical study is a randomized, observer-blind, multicenter study of QIVc versus a non-influenza vaccine in subjects 6...
Background: Some patients with unusual genetic conditions are referred to the National Institutes of Health (NIH). They may not be...
This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with...
This is a multicenter, open-label, single-dose pharmacokinetic (PK) study. Infants, children, and adolescents will receive a single 10 mg/kg dose...
Primary Objectives: - To describe the characteristics of pediatric patients with moderate to severe atopic ...
Multicenter, open-label, non-comparative study to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of osilodrostat in children and adolescent patients with ...
To evaluate the safety and efficacy of fingolimod vs. interferon beta-1a i.m. in pediatric patients with multiple sclerosis (MS)
The study is a Phase 2, multicounty, multicenter, non-confirmatory, investigator- and subject masked, randomized, placebo-controlled study to evaluate the safety,...
This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and...
The study has been designed with two components. Part A is an open label PK study followed by a randomized...
The aim of this study is to evaluate the safety and efficacy of 67Cu-SARTATE in pediatric patients with high-risk neuroblastoma.
Primary Objective: To explore associations between biomarkers of atopic dermatitis (AD) and: -...
Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
Patient are being asked to provide respiratory and blood samples for a clinical research study because the patients have a...
This phase I trial studies the side effects and best dose of nanoparticle albumin-bound rapamycin when given together with temozolomide...
This study is conducted in China only. The purpose is to demonstrate the efficacy and safety of once weekly dosing...
The purpose of this study is to evaluate long-term safety and tolerability data in eligible CLCZ696B2319 (PANORAMA-HF) patients receiving open-label...
The primary objective of the study is to demonstrate the non-inferiority of the antibody response against meningococcal serogroups A, C,...
The primary objective of the study is to demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C,...
Primary Objective: 1. To describe the antibody titers to the antigens (meningococcal serogroups A, C, Y, and ...
The purpose of this study is to provide continued access to rilpivirine (RPV) for participants who were treated with RPV...
Primary Objective: To describe the immune response induced by VRVg-2 and Verorab vaccine at D14 (to assess the ...
Phase 1 - To evaluate the safety and tolerability of REGN10933+REGN10987 compared to placebo ...
The primary purpose of this study is to evaluate the safety and tolerability of ASP0367. This study will also evaluate...
This open-label, single-arm, Phase II multi-center study will enroll approximately 42 subjects and investigate the activity, pharmacokinetics and safety of...
The purpose of this study is to monitor the long-term safety of ustekinumab in pediatric participants (6 years to 17...
The main objective of the study is to evaluate the efficacy of dimethyl fumarate (Tecfidera) and peginterferon beta-1a (Plegridy), both...
This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS)...
This is a two-part, Phase 2, multicenter, open-label, single arm study to evaluate the safety and efficacy of autologous CD30.CAR-T...
To investigate the safety and pharmacokinetics of apixaban in children with congenital or acquired heart disease who have a need...
The purpose of this study is to assess the efficacy of a single (first) dose of 3 fixed doses of...
The purpose of this study in pediatric participants (<18 years of age) with severe hereditary von Willebrand disease (VWD) is: ...
This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged ≥ 2 to <...
Bowel preparation for pediatric colonoscopy.
The purpose of this study is to assess the safety and effectiveness of treatment with once daily (QD) oral administration...
The purpose of this study is to assess the safety and effectiveness of treatment with once daily (QD) oral administration...
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