This is a first-in-human (FIH), open-label, phase 1 dose-escalation study of KN026 in subjects with HER2 positive advanced breast and...
This is an open label, multi-center trial of tisotumab vedotin monotherapy and in combination with bevacizumab, pembrolizumab, or carboplatin in...
This is a Phase 1/2, open-label, multicenter, dose-escalation and expansion study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy...
This is a single arm, Phase II study using the combination of atezolizumab and bevicacizumab in women with advanced, recurrent...
This study evaluates the diagnostic performance and safety of [18F]PSMA-1007 PET/CT imaging in patients with suspected recurrence of prostate cancer...
The purpose of this study is to develop an accurate and useful way of measuring older patients' moods and reactions...
An open-label, Phase 1/2a, study of HPN424 as monotherapy to assess the safety, tolerability and PK in patients with advanced...
Gastric cancer represents a great challenge for health care providers and requires a multidisciplinary context in which surgery plays a...
The purpose of this study is to evaluate the objective response rate (complete response [CR]+ partial response [PR]) of the...
The primary objective of this study is to determine the safety and tolerability of a gene-directed enzyme prodrug therapy for...
This is a study aimed at testing a commonly available and inexpensive chemical (hydrogen peroxide) for efficacy in sensitising large...
This is a phase I, clinical research study of EPI-7386, an investigational drug being studied as a treatment for patients...
Patients with recurrent or metastatic cervical cancer，and will be treated with GLS-010.
This study will determine the pharmacodynamically-active dose of gevokizumab and the tolerable dose and preliminary efficacy of gevokizumab in combination...
DESTINY-Gastric03 will investigate the safety, tolerability, pharmacokinetics, immunogenicity, and preliminary antitumor activity of trastuzumab deruxtecan (T-DXd) alone or ...
This study will compare the efficacy and safety of molecularly-guided therapy versus standard platinum-containing chemotherapy in participants with poor-prognosis cancer...
CCW702 is an investigational immunotherapy for prostate cancer. This is a two-part, first-in-human study to assess the safety and tolerability...
Phase 1/2 dose escalation study to assess the safety and tolerability of ARV-110 in men with mCRPC who have progressed...
This study is a multicenter phase I/II study of the treatment of patients with metastatic prostate cancer. The objective of...
A phase Ib, open-label platform study of select drug combinations chosen in order to characterize safety and tolerability of each...
Fruquintinib once daily in 4 weeks treatment cycle (three weeks on and one week off) in combination with Paclitaxel 80mg/㎡（day1,...
This is an open label, randomized, multicenter, international phase II study for premenopausal patients with hormone receptor positive, HER2 negative...
This is a multi-center, non-randomised Phase 1b study to evaluate the safety and tolerability of ATP128 alone or in combination...
This is a Phase 1 first in human, open label, multi-center, dose escalation study to evaluate the safety, tolerability, PK,...
An open-label, dose escalation and expansion clinical trial to evaluate the safety, tolerability, and PK of fruquintinib in patients with...
Primary Objectives In the Dose Escalation Phase: • To assess the safety and pharmacokinetics (PK)...
This prospective, multicountry, multicentre, non-interventional study plans to include patients who have undergone surgery for early-stage (IA to IIIB on...
This is a two arm Phase III trial in first and second-line HER2 negative patients with locally recurrent or metastatic...
The PREEMPT CRC study is a prospective multi-center observational study to validate a blood-based test for the early detection of...
This study is designed to identify the target Non-Small Cell Lung Cancer (NSCLC) population(s) that over express c-Met (c-Met+) best...
The study comprises two phases: phase I dose escalation (including PK run-in period and treatment period) and phase II study.
The primary objectives of the study in Dose Escalation are to evaluate safety, tolerability, and pharmacokinetics (PK) of REGN5678 alone...
The purpose of the study is to determine whether the combination of talactoferrin, carboplatin and paclitaxel improves progression free survival...
This is a Phase III, randomized, double-blind, placebo-controlled, multi-center international study assessing the activity of durvalumab and chemotherapy administered prior...
The purpose of study is to evaluate the safety, pharmacokinetics, and preliminary efficacy of Amivantamab as a monotherapy and in...
The purpose of this study is to determine whether an investigational immunotherapy nivolumab in combination with ipilimumab or in combination...
English (USA)