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Completed

Study in Japanese Pediatric Subjects With Short Bowel Syndrome (SBS) Who Are Dep...

The purpose of this study is to determine if an investigational treatment (teduglutide) is safe and effective in Japanese children...

Enrolling

Durvalumab and Tremelimumab for Pediatric Malignancies

The purpose of the study is to determine the recommended dose of durvalumab and tremelimumab (immunotherapy drugs) in pediatric patients...

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Enrolling

Safety and Efficiency of Denosumab in Pediatric Subjects With Glucocorticoid-ind...

To evaluate the effect of denosumab on lumbar spine bone mineral density (BMD) Z-score as assessed by dual-energy X-ray absorptiometry...

Enrolling

BAX 111 rVWF in Pediatrics

The purpose of this study in pediatric participants (<18 years of age) with severe hereditary von Willebrand disease (VWD) is: ...

Enrolling

rVWF Pediatric and Adult Study

This study will evaluate the long-term safety and hemostatic efficacy of recombinant von Willebrand factor (rVWF) (vonicog alfa) prophylaxis in...

Enrolling

A Study of Tildrakizumab in Pediatric Subjects With Chronic Plaque Psoriasis

The study has been designed with two components. Part A is an open label PK study followed by a randomized...

Enrolling

Efficacy Study With QIVc in Pediatric Subjects

This phase 3 clinical study is a randomized, observer-blind, multicenter study of QIVc versus a non-influenza vaccine in subjects 6...

Enrolling

Pediatric Patients With Metabolic or Other Genetic Disorders

Background: Some patients with unusual genetic conditions are referred to the National Institutes of Health (NIH). They may not be...

Enrolling

AMG 334 20160172 Pediatric Migraine PK Study.

AMG 334 20160172 Pediatric Migraine PK Study.

Enrolling

Observational Evaluation of Atopic Dermatitis in Pediatric Patients

Primary Objectives: - To describe the characteristics of pediatric patients with moderate to severe atopic ...

Enrolling

Efficacy and Safety of Erenumab in Pediatric Subjects With Episodic Migraine

This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and...

Enrolling

Study to Evaluate a Single Dose of Apixaban in Pediatric Subjects at Risk for a...

CV185118 is a single dose Apixaban PK/PD study in pediatric subjects. The objective of this study is primarily to study...

Enrolling

Telavancin Pediatric PK Study (Ages >3 Months to 17 Years)

This is a multicenter, open-label, single-dose pharmacokinetic (PK) study. Infants, children, and adolescents will receive a single 10 mg/kg dose...

Enrolling

Vedolizumab IV in Pediatric Participants With Ulcerative Colitis (UC) or Crohn's...

The purpose of this study is to evaluate vedolizumab pharmacokinetics (PK), safety and tolerability in pediatric participants with moderately to...

Enrolling

Phase I/II Study of Avelumab in Pediatric Cancer Subjects

This is a multi-center, open-label, international study to evaluate the dose, safety and tolerability, antitumor activity, pharmacokinetic and pharmacodynamics of...

Enrolling

A Study of Risdiplam (RO7034067) in Adult and Pediatric Participants With Spinal...

This is a multi-center, exploratory, non-comparative, and open-label study to investigate the safety, tolerability, PK, and PK/PD relationship of risdiplam...

Enrolling

Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with...

Enrolling

Post-Authorization Safety, Tolerability and Immunogenicity Evaluation of HyQvia...

The purpose of the study is to acquire additional data on safety, tolerability and immunogenicity of HyQvia in pediatric (age...

Enrolling

Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in P...

Multicenter, open-label, non-comparative study to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of osilodrostat in children and adolescent patients with ...

Enrolling

Study of Etelcalceide in Pediatric Subjects With Secondary Hyperparathyroidism a...

Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

Enrolling

Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell...

The purpose of the Phase 2 CSEG101B2201 study is to confirm and to establish appropriate dosing and to evaluate the...

Enrolling

Evaluation of Biomarkers of Atopic Dermatitis in Pediatric Patients (PEDISTAD BI...

Primary Objective: To explore associations between biomarkers of atopic dermatitis (AD) and: -...

Enrolling

Comparison Trial of OPA-15406 Ointment in Pediatric Patients With Atopic Dermati...

To demonstrate the superiority of the investigational medicinal product (IMP; 0.3% OPA-15406 ointment, 1% OPA-15406 ointment, or vehicle) to the...

Enrolling

Long-term Trial of OPA-15406 Ointment in Adult and Pediatric Patients With Atopi...

To demonstrate the safety of 1% OPA-15406 ointment in adult patients with AD and of 0.3% and 1% OPA-15406 ointments...

Enrolling

Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in I...

The primary objective of the study is to demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C,...

Enrolling

Study of Pharmacokinetics, Activity and Safety of Ruxolitinib in Pediatric Patie...

The study is an open-label, single-arm, Phase I/II multi-center study to investigate the PK, activity and safety of ruxolitinib added...

Enrolling

Long-term Safety With Vedolizumab Intravenous (IV) in Pediatric Participants Wit...

The purpose of this study is to determine the safety profile of long-term vedolizumab IV treatment in pediatric participants with...

Enrolling

Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric...

The purpose of this study is to determine if the investigational treatment, MHOS/SHP615, is safe and effective in children with...

Enrolling

Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride...

This phase I trial studies the side effects and best dose of nanoparticle albumin-bound rapamycin when given together with temozolomide...

Enrolling

Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pe...

The purpose of the study is to Evaluate the Effect of Ticagrelor versus Placebo in Reducing the Rate of Vaso-Occlusive...

Enrolling

A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterf...

This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS)...

Enrolling

Study of Safety and Efficacy of CFZ533 in Type 1 Diabetes Pediatric and Young Ad...

The study is a Phase 2, multicounty, multicenter, non-confirmatory, investigator- and subject masked, randomized, placebo-controlled study to evaluate the safety,...

Enrolling

A Safety Study of Ustekinumab in the Treatment of Pediatric Participants Aged 12...

The purpose of this study is to monitor the long-term safety of ustekinumab in pediatric participants (12 years to 17...

Enrolling

CLCZ696B2319E1 OL Extension Study to Evaluate Long-term Safety of Sacubitril/Val...

The purpose of this study is to evaluate long-term safety and tolerability data in eligible CLCZ696B2319 (PANORAMA-HF) patients receiving open-label...

Enrolling

A Roll-over Study With Rilpivirine for Human Immunodeficiency Virus Type 1 (HIV-...

The purpose of this study is to provide continued access to rilpivirine (RPV) for participants who were treated with RPV...

Enrolling

Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When...

Primary Objective: 1. To describe the antibody titers to the antigens (meningococcal serogroups A, C, Y, and ...

Enrolling

Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccin...

The primary objective of the study is to demonstrate the non-inferiority of the antibody response against meningococcal serogroups A, C,...

Enrolling

Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and P...

The main objective of the study is to evaluate the efficacy of dimethyl fumarate (Tecfidera) and peginterferon beta-1a (Plegridy), both...

Enrolling

Activity, Safety and Pharmacokinetics in Pediatric Subjects With Moderate and Se...

This open-label, single-arm, Phase II multi-center study will enroll approximately 42 subjects and investigate the activity, pharmacokinetics and safety of...

Enrolling

A Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagoni...

To investigate the safety and pharmacokinetics of apixaban in children with congenital or acquired heart disease who have a need...

Enrolling

Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccine...

The primary objective of this study is: To demonstrate that VRVg-2 (purified rabies vaccine) is non-inferior to Verorab and Imovax ...

Enrolling

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketam...

The purpose of this study is to assess the efficacy of a single (first) dose of 3 fixed doses of...

Not Yet Enrolling

Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy

Bowel preparation for pediatric colonoscopy.

Not Yet Enrolling

Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Dis...

This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged ≥ 2 to <...

Not Yet Enrolling

A Study to Assess the Safety, Tolerability and Preliminary Efficacy of ASP0367 (...

The primary purpose of this study is to evaluate the safety, tolerability and preliminary efficacy of ASP0367. ...

Not Yet Enrolling

67Cu-SARTATE™ Peptide Receptor Radionuclide Therapy Administered to Pediatric Pa...

The aim of this study is to evaluate the safety and efficacy of 67Cu-SARTATE in pediatric patients with high-risk neuroblastoma.

Not Yet Enrolling

A Phase 2, Double Blind Study to Assess Dexlansoprazole Delayed-Release Capsules...

The purpose of this study is to assess the safety and effectiveness of treatment with once daily (QD) oral administration...

Not Yet Enrolling

A Phase 2 Study of Dexlansoprazole Delayed-Release Capsules to Treat Symptomatic...

The purpose of this study is to assess the safety and effectiveness of treatment with once daily (QD) oral administration...