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Clinical Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Sub...

This clinical study compares the efficacy, safety, and tolerability of therapy with ponesimod vs placebo in subjects with active RMS...

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A Study of Suboptimally Controlled Participants Previously Taking Oral Disease-M...

To evaluate the effectiveness and safety of cladribine tablets in participants with relapsing form of multiple sclerosis (RMS) and active...

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Long-Term Outcomes and Durability of Effect Following Treatment With Cladribine...

The purpose of this study is to explore the long-term outcomes, durability of effect, and real world treatment patterns in...

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A Study of Suboptimally Controlled Participants Previously Taking Injectable Dis...

To evaluate the effectiveness and safety of cladribine tablets in participants with RMS who transition to cladribine tablets after suboptimal...

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Biogen Multiple Sclerosis Pregnancy Exposure Registry

The primary objective of the study is to prospectively evaluate pregnancy outcomes in women with multiple sclerosis who were exposed...

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Dimethyl Fumarate (DMF) Observational Study

The primary objective of the study is to determine the incidence, type, and pattern of serious adverse events (SAEs), including...

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MS PATHS Normative Sub-Study

The primary objective of this study is to determine the normative range of brain volume and brain volume change in...

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Long-term, Open-label, Multicenter Study Assessing Long-term Cardiovascular Risk...

This study will evaluate if patients who had a serious cardiovascular event upon initiation of fingolimod are at risk to...

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Pregnancy Registry Trial

The purpose of the Multi-National Gilenya Pregnancy Exposure Registry in Multiple Sclerosis (MS) is to continuously monitor, evaluate, and assess...

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Phase 1 Study to Evaluate the Safety of ATA188 in Subjects With Progressive and...

The purpose of this study is to evaluate the safety and tolerability of adoptive transfer of ATA188, as a monotherapy...

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Tysabri Observational Program

The primary objective of this study is to assess the long-term safety and impact on disease activity and progression of...

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Pilot Study to Assess the Efficacy & Safety of H.P. Acthar® Gel in Subjects With...

This is a multicenter, multiple dose study to estimate the response rate, and examine the safety of H.P. Acthar® Gel...

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A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterf...

This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS)...

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Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis (RMS)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Interferon-beta-1a (Avonex®), once a...

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Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and P...

The main objective of the study is to evaluate the efficacy of dimethyl fumarate (Tecfidera) and peginterferon beta-1a (Plegridy), both...

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Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Pa...

This is an open-label, multicenter, biomarker study designed to be hypothesis-generating in order to better understand the mechanism of action...

Not Yet Enrolling

Safety and Tolerability of Conversion From Oral or Injectable Disease Modifying...

To assess early phase safety and tolerability of converting patients from approved oral and injectable RMS DMTs to siponimod. The...

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The Reliability, Validity, and Responsiveness of the Static Balance Test in Pati...

The aim of the study is to investigate reliability, validity, and responsiveness of the Static Balance Test in patients with...

Not Yet Enrolling

Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis

The study will evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Interferon-beta-1a (Avonex®), once a week...

Not Yet Enrolling

Study to Evaluate Oral BIIB061 Added to Interferon-beta1 (IFN-β1) in Relapsing M...

The primary objectives of the study are to evaluate the safety of BIIB061 versus placebo in participants with Relapsing Multiple...