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Trial of KN026 in Patients With HER2-positive Advanced Malignant Breast Cancer a...

This is a first-in-human (FIH), open-label, phase 1 dose-escalation study of KN026 in subjects with HER2 positive advanced breast and...

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Breath Analysis to Diagnose Lung Cancer

Determination of volatile organic compounds to discriminate patients with lung cancer from healthy smokers and non-smokers healthy subjects.

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An Open Label Study of Bavituximab and Pembrolizumab in Advanced Gastric and GEJ...

This study evaluates the combination of bavituximab and pembrolizumab in the treatment of gastric and gastroesphogeal cancer. All patients will...

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Study of Adjuvant ONO-4538 With Resected Gastric Cancer

The purpose of study is to evaluate the efficacy and safety of postoperative adjuvant chemotherapy with Nivolumab in combination with...

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A Study of ZN-c5 in Subjects With Breast Cancer

This is a Phase 1/2, open-label, multicenter, dose-escalation and expansion study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy...

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Phase II Study of Atezolizumab + Bevacizumab in Endometrial Cancer

This is a single arm, Phase II study using the combination of atezolizumab and bevicacizumab in women with advanced, recurrent...

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A Study of ZN-c5 in Participants With Breast Cancer

This is a Phase 1 open-label, multicenter study to evaluate biomarkers for ZN-c5 in subjects with breast cancer

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A Pilot Study of BXCL701 in Patients With Pancreatic Cancer

A study to assess the biochemical and immunomodulatory effects of BXCL701 in pancreatic cancer.

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A Study to Test Combination Treatments in Patients With Advanced Gastric Cancer

The purpose of this study is to determine whether Nivolumab in combination with other therapies is more effective than Nivolumab...

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A Study of Neoadjuvant Nivolumab + Palbociclib + Anastrozole in Post-Menopausal...

A randomized multi-arm study evaluating the safety and efficacy of palbociclib and anastrozole with or without nivolumab in participants with...

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Study of NGM120 in Subjects With Advanced Solid Tumors and Pancreatic Cancer Usi...

Study of NGM120 in subjects with advanced solid tumors and pancreatic cancer.

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Identifying and Measuring Depression in Older Cancer Patients

The purpose of this study is to develop an accurate and useful way of measuring older patients' moods and reactions...

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Study of HPN424 in Patients With Advanced Prostate Cancer

An open-label, Phase 1/2a, study of HPN424 as monotherapy to assess the safety, tolerability and PK in patients with advanced...

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Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer

Background: - Researchers are studying types of thyroid cancer that seem to cluster in families. ...

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An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With...

The purpose of this study is to evaluate the objective response rate (complete response [CR]+ partial response [PR]) of the...

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A Phase I Gene Therapy Study of FP253/Fludarabine for Prostate Cancer

The primary objective of this study is to determine the safety and tolerability of a gene-directed enzyme prodrug therapy for...

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KORTUC Phase II - Intra-tumoural Radiation Sensitizer in Patients With Locally A...

This is a study aimed at testing a commonly available and inexpensive chemical (hydrogen peroxide) for efficacy in sensitising large...

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Oral EPI-7386 in Patients With Metastatic Castration-Resistant Prostate Cancer

This is a phase I, clinical research study of EPI-7386, an investigational drug being studied as a treatment for patients...

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Study of Nivolumab Plus Ipilimumab, Ipilimumab or Cabazitaxel in Men With Metast...

The purpose of this study is to determine whether nivolumab plus ipilimumab has preliminary evidence of safety and effectiveness in...

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Study of GLS-010 Injection in Patients With Recurrent or Metastatic Cervical Can...

Patients with recurrent or metastatic cervical cancer,and will be treated with GLS-010.

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Robotic, Laparoscopic and Open Surgery for Gastric Cancer Compared on Surgical,...

Gastric cancer represents a great challenge for health care providers and requires a multidisciplinary context in which surgery plays a...

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Study of IMP4297 in Patients With BRCA1/2 Mutation Ovarian Cancer

A phase II, multi-center, open-label, single-arm, non-randomized study to evaluate the efficacy, safety and tolerability of IMP4297 capsules in subjects...

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Clinical Evaluation of a Test for Monitoring the Recurrence of Bladder Cancer

The objective of this study is to establish the performance characteristics of an assay that detects the recurrence of bladder...

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Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorecta...

This study will determine the pharmacodynamically-active dose of gevokizumab and the tolerable dose and preliminary efficacy of gevokizumab in combination...

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MEN1611 With Trastuzumab (+/- Fulvestrant) in Metastatic Breast Cancer

The main purpose of this open-label, dose-escalation, phase Ib study is to identify the appropriate dose of MEN1611 to be...

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A Randomized Phase 2/3 Multi-Center Study of SM-88 in Patients With Metastatic P...

A prospective, open-label phase 2/3 trial in metastatic pancreatic cancer subjects who have failed two lines of prior systemic therapy....

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The Combination of GX-188E Vaccination and Pembrolizumab in Patients With HPV 16...

A Multi-Center, Open-label Phase Ib-II Trial of the Combination of GX-188E Vaccination and Pembrolizumab in Patients with Advanced, Non-Resectable HPV-Positive...

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A Study of Nivolumab and Ipilimumab in Combination With Transarterial ChemoEmbol...

The purpose of this study is to compare effectiveness and safety of nivolumab with and without ipilimumab in combination with...

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An Investigational Immunotherapy Study of Nivolumab in Combination With Rucapari...

The purpose of this study is to assess the safety and efficacy of nivolumab in combination with rucaparib, docetaxel, or...

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A Phase I Study of FCN-411 in Advanced Non-small Cell Lung Cancer Chinese Patien...

This phase I trial with dose-escalation stage and dose-expansion stage is the first-in-human study of FCN-411, a drug being developed...

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A Study of IMP4297 as Maintenance Treatment Following First-line Chemotherapy in...

IMP4297 is a PARP inhibitor. This is a 2:1 randomized, double-blind, placebo-controlled study conducted in patients with advanced (FIGO Stage...

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Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Patien...

The primary objectives of the Dose Escalation Phase are to assess the safety and pharmacokinetics (PK) in order to determine...

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A Phase II Randomized Study Comparing the Efficacy and Safety of Targeted Therap...

This study will compare the efficacy and safety of molecularly-guided therapy versus standard platinum-containing chemotherapy in participants with poor-prognosis cancer...

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Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participan...

Study consists of an open-label, safety run-in part and a randomized, double-blind, placebo-controlled Phase 2/3 part. In the Phase 2/3...

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A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/M...

This is a Phase 2, global, multicenter, open label, single arm study designed to evaluate the efficacy, safety, tolerability, pharmacokinetic...

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Study of Peposertib in Combination With Capecitabine and Radiotherapy in Rectal...

The main purpose of the study is to define maximum tolerated dose (MTD), recommended Phase II dose (RP2D) of Peposertib...

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A Study to Evaluate U3-1402 in Subjects With Advanced or Metastatic Colorectal C...

This study is designed to primarily evaluate the safety and efficacy of U3-1402 in participants with advanced or metastatic colorectal...

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A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic B...

A phase Ib, open-label platform study of select drug combinations chosen in order to characterize safety and tolerability of each...

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First-in-human Study of CCW702 in Patients With Metastatic Castration Resistant...

CCW702 is an investigational immunotherapy for prostate cancer. This is a two-part, first-in-human study to assess the safety and tolerability...

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FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cance...

The goal of this research is to test the accuracy of PET/MRI imaging with 18F-fluorofuranylnorprogesterone (FFNP) for measuring progesterone receptor...

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A Study on the Safety and Efficacy of LAE001 in the Treatment of Metastatic Pros...

This study is a multicenter phase I/II study of the treatment of patients with metastatic prostate cancer. The objective of...

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Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cance...

Phase 1/2 dose escalation study to assess the safety and tolerability of ARV-110 in men with mCRPC who have progressed...

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Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With...

NuTide:121 compares NUC-1031 with gemcitabine, both in combination with cisplatin, in patients with previously untreated advanced biliary tract cancer. ...

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A Phase III Study of Fruquintinib in Combination With Paclitaxel in Second Line...

Fruquintinib once daily in 4 weeks treatment cycle (three weeks on and one week off) in combination with Paclitaxel 80mg/㎡(day1,...

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Phase 1b Study to Evaluate ATP128, With or Without BI 754091, in Patients With S...

This is a multi-center, non-randomised Phase 1b study to evaluate the safety and tolerability of ATP128 alone or in combination...

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Phase 1 Study of SL-172154 (SIRPα-Fc-CD40L) in Subjects With Ovarian Cancer

This is a Phase 1 first in human, open label, multi-center, dose escalation study to evaluate the safety, tolerability, PK,...

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A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors, Colorectal, an...

An open-label, dose escalation and expansion clinical trial to evaluate the safety, tolerability, and PK of fruquintinib in patients with...