For Healthcare Professionals

Avacostar - (PASS)

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About the study

The Avacostar PASS is a non-interventional, multi-national, prospective cohort study that will collect data from 2 cohorts of patients: those treated with avacopan for active severe AAV, and a second cohort treated with a cyclophosphamide or rituximab-based induction regimen without avacopan for active severe AAV. The overall study duration is anticipated to be up to 7 years, including a recruitment period of approximately 3 years.
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Who can take part

You may be eligible to participate in the study if you meet the following criteria:

INCLUSION CRITERIA

Inclusion Criteria:

  1. Diagnosis of AAV (MPA or GPA), as determined by the Investigator according to their usual practice.
  2. Active, severe AAV at the time of commencing avacopan or non-avacopan SoC induction therapy, in the opinion of the Investigator.
  3. Age ≥18 years of either sex.
  4. Has provided written informed consent.
  5. Has commenced within the previous 6 months, or is planned to commence avacopan, cyclophosphamide or rituximab for the treatment of severe, active AAV outside of an interventional clinical study.

EXCLUSION CRITERIA

Exclusion Criteria:

• Concurrent participation in an interventional study, unless prospectively discussed and agreed with the Medical Monitor.

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Study Locations

Enter your ZIP code/Postal code/PIN code to locate study sites near you:

How to Apply


Contact the study center to learn if this study is a good match for you.
Phone iconCall +41 58 851 80 00Email iconEmail Study Center

Study Details


Contition

ANCA-associated Vasculitis

Age

18+

Participants Needed

500

Est. Completion Date

Dec 1, 2030

Treatment Type

OBSERVATIONAL


Sponsor

Vifor Fresenius Medical Care Renal Pharma

ClinicalTrials.gov NCT Identifier

NCT05897684

Study Number

CS-AVA-2022-0016

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