INTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)
About the study
The purpose of this observational study is to collect data on the natural history of disease of patients with Hemophagocytic Lymphohistiocytosis (HLH) including diagnosis, treatments, responses, and outcomes.
Who can take part
You may be eligible to participate in the study if you meet the following criteria:
INCLUSION CRITERIA
Inclusion Criteria:
- Patients with clinically suspected or confirmed HLH, including those meeting the HLH-2004 diagnostic criteria (primary or secondary forms, including malignancy) and other forms of HLH (macrophage activation syndrome [MAS], cytokine release syndrome [CRS], etc.)
- Signed and dated informed consent and assent (adolescents)
EXCLUSION CRITERIA
Exclusion Criteria:
* None
Study Locations
Enter your ZIP code/Postal code/PIN code to locate study sites near you:
How to Apply
Contact the study center to learn if this study is a good match for you.
Study Details
Contition
Hemophagocytic Lymphohistiocytoses
Participants Needed
200
Est. Completion Date
Jan 31, 2026
Treatment Type
OBSERVATIONAL
Sponsor
Children's Hospital Medical Center, Cincinnati
ClinicalTrials.gov NCT Identifier
NCT05277272
Study Number
Sobi.HLH-RWE102
Understanding Clinical Trials
Get answers to your questions about clinical trials.What is clinical research?What does taking part in clinical trials involve?What should I ask the trial doctor?