[No standalone website (unbranded, no questionnaire)] A Study of Subjects With Psoriatic Arthritis to Investigate the Effectiveness of Adalimumab Introduction Compared With Methotrexate Dose Escalation (CONTROL)

How to apply

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Study’s contact

Call center

888-662-6728 (U.S. and Canada)

Email address

global-roche-genentech-trials@gene.com

Condition

Crohn Disease

Treatment type

Interventional

Investigational product

Etrolizumab

Phase

Phase 3

Sponsor

Hoffmann-La Roche

ClinicalTrials.gov identifier

NCT02403323

Study number

GA29145

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About the study

This open-label extension and safety monitoring study is composed of two parts: Part 1 will evaluate the long-term safety and efficacy of continued etrolizumab treatment in participants with moderately to severely active Crohn's disease who were previously enrolled in the etrolizumab Phase III Study GA29144 (NCT02394028) and who meet eligibility criteria for enrollment into Part 1. In Part 2, participants who have stopped etrolizumab treatment (either by exiting Part 1 of this study or by entering directly from Study GA29144 [NCT02394028]) will be monitored for 92 weeks for progressive multifocal leukoencephalopathy (PML) and other safety events.

Who can take part?

You may be eligible to participate in the study if you meet the following criteria:

Inclusion criteria
  1. NCT02394028) who meet the eligibility criteria for open-label etrolizumab as described in the protocol Part 2 Safety Monitoring: - Patients who participated in etrolizumab Phase III study GA29144 (
  2. NCT02394028) and are not eligible or choose not to enter Part 1 - Patients who transfer from Part 1 - Completion of the 12-week safety follow-up period prior to entering
Exclusion criteria

For a full list of inclusion/exclusion criteria, please visit ClinicalTrials.gov

Study locations

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How to apply

Determine if a study site for this clinical trial is near you. Contact the study to apply.

Find a Study Site